Herbal Mall Kishor Gugal Guggul is used classically to purify blood and reduce inflammation. It is the oleo-gum-resin exudate from the bark of Commiphora wightii. It is very well described in various ayurvedic texts for their various therapeutic properties. C. wightii has been used as an inactive pharmaceutical ingredient, binding agent, anti-obesity agent and cholesterol-reducing agent. Gum guggul is used in incense, lacquers, varnishes, and ointments, as a fixative in perfumes, and in medicine. Therapeutic uses include treatment of nervous diseases, leprosy, muscle spasms, ophthalmia, skin disorders, ulcerative pharyngitis, hypertension, ischaemia, and urinary disorders.
The main active constituents of this oleo-gum resin are Z-guggulsterone, E-guggulsterone, Z-guggulsterol and guggulsterol I-V. The main aim of chemical investigations was to isolate and chemically characterize compounds of the oleo-gum resin of C. wightii responsible for the hypocholesterolaemic/hypolipaemic activity. For the standardization of it, tests like physico-chemical values, chromatographic analysis have been reported.
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